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            Cell Therapy Research Solutions

            Cell Therapy Enablement

            New cell-based therapies are ready to transform medicine by providing highly personal and effective treatments. Cancer and spinal cord injury therapies are just two areas where clinical trials are showing promising results.

            As a leader in cell analysis and isolation, BD is uniquely positioned to help researchers and developers address the emerging needs in this rapidly advancing field.

            Cell therapy development and production is complex and demands the highest standards in safety and efficacy. BD’s wide portfolio of current and soon to be released cell analyzers brings a history of superior quality and the ability to reveal the identity and function of billions of cells, one at a time.

            A key challenge in cell therapy development today is the purity of cell preparations. Diluted or impure cell populations can be less efficacious, and unwanted cells may present safety concerns. Combining droplet-based flow cytometry with BD's proven FACS™ technology provides the highest grade of purity achievable today, enabling:

            • ≥98% purity for many applications
            • Multiparameter isolation of complex phenotypes

            Our custom multicolor cell sorting reagents can be tested for sterility, toxicity, and lack of microbial or viral contamination and manufactured in cGMP compliance. Lyophilization for longer shelf life is available upon request.

            BD holds a license to US patent number 7,947,464 which describes methods for identifying regulatory T cells and includes the use of CD127, CD25 and CD4. Please contact  bdlicensing@bd.com for sub-licensing information.

            BD Influx™ cell sorter

            • Highly customizable
            • Up to 10 lasers and 24 parameters
            • Multiple nozzle sizes
            • Class II Type A2 BSC available
            • Aseptic replaceable fluidics

            New BD Cytopeia™ fluidic kit

            • Improved kit design (SAL of 10-6)
            • New sterile sheath bag with DPBS
            • Optional sterile in-line sheath filter
            • Sheath tank
            • Available for BD Influx and BD FACSJazz

            Custom cGMP reagents for cell isolation

            Specificity Clone Format
            CD4 (L200) PerCP
            CD25 (2A3) APC
            CD127 (40131) PE

            Please contact  bdb_custom_orders@bd.com

            In-depth characterization of cell populations and discovery of biomarkers remain central to the successful development of safe and efficacious cell therapies. Flow cytometry represents a unique technology platform in this context, providing high-content information at the single cell level based on surface markers and intracellular characteristics.

            BD is recognized as a leader in this field with best-in-class fluorescent dyes and instrumentation and a broad antibody portfolio. BD software, setup and control reagents, in combination with its high-quality reagents and instrumentation, enables the highest level of standardization in cell therapy.


            Instrumentation

            BD FACSLyric™

            High performance integrated solution for accurate, reliable  
            and repeatable results across users, instruments, and sites.

            BD FACSVia™

            A powerful benchtop system designed to ensure accuracy,  
            repeatability, and ease-of-use.

            BD FACSCanto™

            Cell analyzer with proven reliability and high-quality results  
            supporting up to 10 parameters.

            Cell Characterization Antibodies for Cell Therapy Development

              Regulatory Status Format Product Highlights
            Single vials RUO or RUO GMP Liquid
            • >6,000 directly conjugated RUO antibodies (ISO certified)
            • >300 directly conjugated RUO GMP antibodies
            • Innovative dye technology developed by Sirigen provides brighter dye options for better cell separation and easier multicolor analysis
            Custom antibody cocktails RUO or RUO GMP
            • Liquid or lyophilized
            • In vials or 96-well plates
            BD™ Lyoplate format flexibility permits user-defined experiment layouts, including the exact content of each well within the plate

            BD has been a pioneer and a trusted partner of leading biopharmaceutical companies around the world. As a result, our products are used in the manufacture of more than 110 animal and human health biopharmaceuticals on the market today. Leveraging our experience in developing cell culture media, supplements and feeds, we are now working on cost-effective cell therapy expansion media to help you achieve optimal and consistence performance.


            MSC Media

            Our proprietary Mesenchymal Stem Cell (MSC) serum-free expansion medium optimizes performance to deliver more cell doublings per passage without refeeding, while maintaining normal MSC phenotype and function.  .

            Media 天津体育彩票网

            Our experience, combined with our proven methodology and extensive analytical capabilities, allows us to provide customers with customized cell therapy expansion medium solution.

            Media Manufacturing

            As part of BD’s global network of manufacturing centers, BD is focused on the development and manufacturing of media and supplements.

            • Small-scale, rapid medium production
            • GMP production
            • Animal-free, antibiotic-free facility
            • Compliant with 21 CFR Parts 210 and 211 regulations for the manufacture of finished pharmaceuticals
            • ISO 9001 certified

            Class 1 Laser Product.

            Unless otherwise noted, For Research Use Only. Not for use in diagnostic or therapeutic procedures.

            The BD FACSLyric™ flow cytometer is for In Vitro Diagnostic Use with BD FACSuite™ Clinical software for up to 6 colors.

            The BD FACSLyric™ flow cytometer is for Research Use Only with BD FACSuite™ software for up to 12 colors.

            The 12-color BD FACSLyric™ flow cytometer is for Research Use Only.

            The BD FACSVia™ flow cytometer and BD FACSCanto™ flow cytometer is for In Vitro Diagnostic Use.

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